I too have had trouble with Launchbar 6.7.2 ever since I upgraded to Mac OS Sierra (10.12.x). Each time I unlock the screen and try the Cmd-Spacebar to open it and start typing, it acts like Lauchbar is still asleep. The command line prompt appears right away but typing and getting a response to what I type or enter is like super slow to respond. I don't know what it is doing but I have to wait for 20-40 sec, maybe longer (haven't timed it). It appears to occur only the first time per session, like it's doing a quick indexing or something. It used to be so fast and responsive but this first time after a computer display sleep is not acceptable for me.
BTW, I leave the computer powered up all the time and the hard drive on all the time. The display I sleep after 15 min or so with screen lock.